This outsourcing of labor is possible thanks to the emergence and widespread proliferation of automated DNA sequencing instruments, which can accomplish in one day what would take a whole team of ...

In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

In 1986, the California Institute of Technology (CIT) announced the development of a semi-automated machine for sequencing DNA. This machine significantly accelerated the process of mapping and ...

The PippinHT system serves as an automated tool for DNA size selection in NGS applications. Leveraging the company's esteemed sizing technology, PippinHT enhances throughput to 24 samples per run, a ...

Next-generation sequencing (NGS) has become a widely used and developed method in research 1. NGS plays a crucial role in diagnostics, especially for cancer, as the methodology allows sensitive ...

In the early 1980s, Dr. Caruthers invented an efficient, automated technology for synthesizing DNA that remains the leading method today. The chemical reactions that Caruthers discovered accurately ...

Despite these advances, the synthesis of DNA nanostructures has remained a largely manual and time-consuming process. Traditional approaches often require the precise mixing of hundreds of unique DNA ...

Johan Strömqvist, PhD, has always been interested in “seeing” molecules, particularly in three dimensions (3D). Strömqvist worked with optical single-molecule imaging for his PhD and then founded a ...

A group of a few dozen colorful translucent 3D blobs, many of which overlap, contain brightly colored dots against a black background. Three-dimensional transcriptomics data from an instrument ...

The landscape of next-generation sequencing (NGS) continues to be defined by astonishing technological progress. We continue to witness sequencer throughput expansion with systems like the Illumina ...

Current approaches to mapping fork progression in the human genome suffer from drastically low throughput. Here, we introduce ForkML, a nanopore sequencing-based method automatically positioning ...