Complement Factor H (CFH) is a pivotal regulator of the complement system, integral to maintaining immune homeostasis and protecting host tissues from undue complement‐mediated damage. By inhibiting ...

The immune system is our frontline protection against infection, continually searching for and destroying unknown pathogens.

Immune checkpoint blockade (ICB) has reshaped modern immunotherapy by unleashing antitumor immune responses through targeting inhibitory immune checkpoints ...

Researchers from the University of Osaka have identified a novel antibody mechanism, called immune-induced TCR-like antibodies (iTabs), that can selectively suppress overactive immune responses. In ...

A team has identified a previously unknown phase of the immune response. The results challenge long-standing assumptions about the process called 'T-cell priming'. These new insights have significant ...

Accurate measurement of HMGB-1, neopterin and sIL-2R supports reliable assessment of immune activation across clinical and ...

A collaborative research team from Jilin University, Tongji Hospital of Huazhong University of Science and Technology, and the Institute of Zoology, Chinese Academy of Sciences, has demonstrated that ...

An MUSC research team reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that contribute to fetal brain inflammation and ...

Our immune system works all the time to protect us from harmful bacteria, viruses, and injuries. It is a complex system made ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and autoimmune conditions when it turns against the body. The protein, Granzyme K, ...