How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

For adults aged 50 years or older, an investigational messenger RNA (mRNA)-based vaccine (mRNA-1010) is superior to ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different ...

Researchers decoded how mRNA is transported in Ustilago maydis cells. They identified how binding motifs ensure accurate ...

A stabilized mRNA carrier turns tumor injection into broader immune activation by extending vaccine delivery to lymph nodes ...

Myocarditis is recognized as a rare but serious adverse reaction to messenger RNA (mRNA) vaccination against COVID-19.

Regulatory filings are under review in the U.S., Europe, Canada and Australia, with potential approvals expected to ...