Phys.org

Boosting precision gene editing: Autophagy shifts DNA repair toward homologous recombination

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...
Cal Alumni Association

How Do Social Structures Shape Your Well-Being?

Systemic, structural change has always been a part of the perspective of the Greater Good Science Center. In a 2022 essay, editor Jeremy Adam Smith defines structural forces in the context of our work ...
eLife

Study reveals intricate molecular detail of human DNA repair process

The research, published today as a Reviewed Preprint in eLife, is described by the editors as a landmark study with compelling evidence on how an important player in DNA repair – the RAD51 filament – ...
IEEE

WeightAln: Weighted Homologous Alignment for Protein Structure Property Prediction

Abstract: Accurately predicting protein structure properties is essential in analyzing the structure and function of a protein, such as secondary structure, solvent accessibility, and dihedral angles.
Frontiers

Prostruc: an open-source tool for 3D structure prediction using homology modeling

Homology modeling is a widely used computational technique for predicting the three-dimensional (3D) structures of proteins based on known templates,evolutionary relationships to provide structural ...
Newsweek

Mars: Mysterious ‘Dense Structures’ Detected Below Planet’s Surface

See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Researchers have found bizarre, enormous structures hidden deep beneath ...
Smithsonian Magazine

Scientists Are Investigating a Puzzling Underground ‘Anomaly’ Near the Giza Pyramids

Researchers used ground-penetrating radar and electrical resistivity tomography to scan the graveyard near the Great Pyramid of Khufu. Archaeological Prospection Without breaking ground, ...
Phys.org

Researchers study the intricacies of homologous recombination and abnormal chromosome bridges

Keeping the genetic information stored in genomic DNA intact during the cell division cycle is crucial for almost all lifeforms. Extensive DNA damage invariably causes various adverse genomic ...
ascopubs.org

Homologous recombination repair gene mutation (HRRm) testing patterns and treatment selection from a real-world cohort of patients with metastatic castration-resistant prostate ...

11-Ketotestosterone and time to castration resistance in patients with recurrent non-metastatic prostate cancer receiving androgen deprivation therapy. This is an ASCO Meeting Abstract from the 2024 ...
ascopubs.org

RNA-Based Homologous Recombination Deficiency Signature Detects Homologous Recombination Deficiency-RNA+ Patients With and Without Homologous Recombination Repair Gene ...

Homologous recombination deficiency (HRD) is a well-described phenotype of some prostate cancers; however, current biomarkers for HRD are imperfect and rely on detection of single gene alterations in ...
The New York Times

In Business, ‘Flat’ Structures Rarely Work. Is There a Solution?

Companies that have rejected hierarchies have typically lacked diversity and, in at least one case, faced scandal. A new crop of them is aiming to find a middle ground. By Charlie Brinkhurst-Cuff ...